Journal
THROMBOSIS AND HAEMOSTASIS
Volume 90, Issue 3, Pages 377-384Publisher
SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN
DOI: 10.1160/TH03-05-0268
Keywords
CD40L; atherothrombotic disease; platelets; extracellular matrix; matrix metalloproteinase
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Recent data suggests that CD40L is involved in the pathogenesis of atherothrombotic disease. This review will focus on the history of CD40L, its role in platelet-mediated pathogenesis of atherothrombotic disease, its association to clinical syndromes and procedures, and its role in determining plaque rupture.
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