Journal
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
Volume 58, Issue 3, Pages 285-289Publisher
WILEY
DOI: 10.1046/j.1365-3083.2003.01314.x
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Natural autoantibodies (NAbs), produced by B-1 B-cells, are directed against autoantigens and pathogens. NAbs can capture and present antigen to T helper cells thereby initiating adaptive immunities. It is proposed that screening for NAbs against pathogens will predict the strength of an antigen-induced immune response and could be used as a tool for vaccine development.
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