Journal
OPTICS LETTERS
Volume 28, Issue 17, Pages 1546-1548Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.28.001546
Keywords
-
Categories
Funding
- NHLBI NIH HHS [HL25934] Funding Source: Medline
Ask authors/readers for more resources
Contrast agents are utilized in virtually every imaging modality to enhance diagnostic capabilities. We introduce a novel class of optical contrast agent, namely, encapsulating microspheres, that are based not on fluorescence but on scattering nanoparticles within the shell or core. The agents are suitable for reflection- or scattering-based techniques such as optical coherence tomography, light microscopy, and reflectance confocal microscopy. We characterize the optical properties of gold-, melanin-, and carbon-shelled contrast agents and demonstrate enhancement of optical coherence tomography imaging after intravenous injection of such an agent into a mouse. (C) 2003 Optical Society of America.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available