Journal
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY
Volume 29, Issue 7, Pages 588-593Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/S0748-7983(03)00109-4
Keywords
surgery; cancer; cardia; oesophageal resection
Ask authors/readers for more resources
Aims: The optimal extent of oesophageal resection and surgical approach in patients treated for adenocarcinomas of the oesophagogastric junction (OGJ) are still uncertain. We report the correlations between resection margin involvement and outcome. Methods: Patients with positive proximal resection margin (PPRM) and those with negative proximal resection margin (NPRM) were compared. Results: Of 94 patients with macroscopically complete resection, eight were PPRM. There was no difference between the two groups in postoperative mortality or morbidity rates, in anastomotic leakage or in recurrence rates. The median survival in the PPRM group was 11.1 months compared with 36.3 months in the NPRM group (P = 0.02). No infiltration was observed in patients whose proximal margin exceeded 7 cm. The extended transthoracic approach was the only prognostic factor for tumours type 11 (P = 0.03, RR = 1.4, 95% CI: 1.1-1.8). Conclusion: Histologic infiltration of oesophageal resection margin influences 5-year survival rate. In adenocar nomas of the OGJ that can be treated curatively, a transection with a 8 cm oesophagectomy above the tumour in fresh specimen should be performed, and by thoracoabdominal approach for tumours type I and II. (C) 2003 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available