New cembrane diterpenes of the marine octocoral Eunicea tourniforti from the eastern Caribbean

An investigation of the Caribbean octocoral Eunicea tourniforti collected along the southwest coast of Barbados afforded four new cembrane diterpenes, 1, 2, 4, and 5, along with the known cembranolide 3. The structures of all metabolites were determined by spectroscopic methods. Seasonal effects-on the secondary metabolite content of the specimens collected were also observed.