Gender dfferences in binge-eating: a population-based twin study

Objective: To assess whether genetic and environmental effects on liability to binge-eating ( BE) are of equal importance for males and females and whether the same genetic risk factors predispose to BE in the two sexes. Method: Questionnaire data on 8045 same sex and opposite sex twins, aged 19 - 31 years, from a population-based Norwegian registry, was used to estimate the relative contribution of genetic and environmental factors to liability for BE utilizing structural equation modeling. Results: In the best-fitting model, the magnitude of genetic and environmental effects on BE was the same for males and females. Heritability was 51%. The correlation between genetic risk factors in men and women was estimated to be + 0.57. Conclusion: Binge-eating appears to be equally heritable in males and females. Although the majority of the genetic risk factors are shared between the sexes, there may exist gender-specific genetic effects on liability.