Journal
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
Volume 97, Issue 5, Pages 539-541Publisher
ROYAL SOC TROPICAL MEDICINE
DOI: 10.1016/S0035-9203(03)80018-4
Keywords
onchocerciasis; Onchocerca volvulus; diagnosis; detection; immunochromatographic test; enzyme-linked immunosorbent assay; Mexico
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There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasis elimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were compared in a Mexican population with onchocerciasis. The sensitivity of the ELISA and ICT was 97% and 86%, respectively.
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