Journal
BIOMACROMOLECULES
Volume 4, Issue 5, Pages 1250-1254Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm030022o
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A Michael reaction of chitosan was conducted in water containing acetic acid with various acryl reagents. The degree of substitution could be controlled by temperature, reaction time, and the amount of acryl reagents. Although the modified chitosan derivatives with acrylic acid esters showed water-solubility, that with poly(ethylene glycol) acrylate, however, turned to water-insoluble material by lyophilization. Good biodegradation was observed in modified chitosan derivatives by standard activated sludge.
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