Journal
CLINICAL AND EXPERIMENTAL MEDICINE
Volume 3, Issue 3, Pages 140-149Publisher
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s10238-003-0017-9
Keywords
hematopoietic stem cell; mesenchymal stem cell; xenotransplantation model; nonobese diabetic/severe combined immunodeficient mice; fetal sheep; plasticity; transdifferentiation
Categories
Funding
- NHLBI NIH HHS [R01 HL64856-01] Funding Source: Medline
Ask authors/readers for more resources
The bone marrow is constituted of two separate and distinct stem cells. The hematopoietic stem cells (HSC) are responsible for the production and maintenance of all the mature blood cells. The mesenchymal stem cells constituted the bone marrow stroma. In this report we review our current understanding on both stem cell populations. We also discuss the recent unexpected degree of differentiation plasticity that have been reported recently and the impacts these new discoveries may have in stem cell therapy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
