4.7 Article

Ellagitannin chemistry. Studies on the stability and reactivity of 2,4-HHDP-containing glucopyranose systems

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 68, Issue 19, Pages 7433-7438

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo034495x

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Funding

  1. NIGMS NIH HHS [GM35727] Funding Source: Medline

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The synthesis of a 2,4-HHDP containing glucopyranose ellagitannin model system has been achieved. Attempts to prepare a related target bearing a 1,6 bridge led instead to the discovery of a likely strain-driven tautomerization to cyclohexadienone intermediates.

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