Journal
TETRAHEDRON LETTERS
Volume 44, Issue 40, Pages 7441-7443Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2003.08.036
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A novel palladium-catalysed three component cascade process is described involving carbonylation of all aryl iodide to generate an acyl palladium species which is intercepted by a primary aliphatic/aromatic amine, amide or sulfonamide followed by intramolecular Michael addition to afford 3-substituted isoindolin-1-ones in good yield. (C) 2003 Elsevier Ltd. All rights reserved.
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