Journal
ARCHIVES OF MICROBIOLOGY
Volume 193, Issue 10, Pages 693-699Publisher
SPRINGER
DOI: 10.1007/s00203-011-0739-0
Keywords
Fire blight; Desferrioxamine; Ferrioxamine; Siderophore biosynthesis
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Funding
- Swiss Secretariat for Education and Research [SBF C07.0038]
- Swiss Federal Office for Agriculture (BLW Fire Blight Research-Pathogen)
- European Science Foundation research network [864]
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Genomics has clarified the biosynthetic pathway for desferrioxamine E critical for iron acquisition in the enterobacterial fire blight pathogen Erwinia amylovora. Evidence for each of the individual steps and the role of desferrioxamine E biosynthesis in pathogen virulence and cell protection from host defenses is presented. Using comparative genomics, it can be concluded that desferrioxamine biosynthesis is ancestral within the genera Erwinia and Pantoea.
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