Journal
TRENDS IN CELL BIOLOGY
Volume 13, Issue 10, Pages 510-516Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2003.08.005
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Funding
- NCRR NIH HHS [1P20 RR 15569-02] Funding Source: Medline
- NIGMS NIH HHS [GM 63862] Funding Source: Medline
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The recently identified Alb3/Oxa1/YidC family constitutes a novel class of proteins that function in promoting membrane insertion in chloroplasts, mitochondria and bacteria. These proteins mediate membrane insertion of a diverse group of membrane proteins that range from phage coat proteins in bacteria and respiratory-chain protein subunits in mitochondria to the light-harvesting chlorophyll-binding proteins in chloroplasts. Here, we discuss the Alb3/Oxa1/YidC protein family and their possible function as membrane chaperones, helping newly synthesized proteins to fold into the membrane bilayer.
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