Journal
HAUTARZT
Volume 54, Issue 10, Pages 970-973Publisher
SPRINGER
DOI: 10.1007/s00105-003-0585-3
Keywords
contact dermatitis; anal eczema; Palmar eczema; moist toilet paper; iodopropynyl butylcarbamate
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A 63-year old man developed severe perianal and palmar contact dermatitis caused by sensitization to iodopropynyl butylcarbamate in moist sanitary wipes. Iodopropynyl butylcarbamate is increasingly employed as preservative in common cosmetic formulations and moist sanitary wipes as substitute for the previously frequently used sensitizers isothiazolinones and methyldibromoglutaronitrile. The allergic potential of diverse preservatives is a serious problem for the cosmetic industry, since truly hypoallergenic preservatives are not available but products such as moist sanitary wipes in large packages definitely require some form of protection.
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