Journal
INFECTION AND IMMUNITY
Volume 71, Issue 10, Pages 6045-6048Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.71.10.6045-6048.2003
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Interleukin-15 (IL-15) transgenic mice which had been inoculated with Mycobacterium bovis bacillus Calmette-Guerin (BCG) 24 weeks previously showed resistance against airborne infection with Mycobacterium tuberculosis H37Rv accompanied by an increased CD8(+)-Tcl-cell response. IL-15 may be used as an immune adjuvant given with BCG vaccination to enhance its biologic efficacy.
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