Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 13, Issue 5, Pages 589-594Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2003.09.008
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Methods for the chemical synthesis of proteins have advanced considerably over the past decade. In many instances, laboratory synthesis can now be considered a viable alternative to ribosomal biosynthesis, especially when custom modifications of a protein are desired; chemical approaches guarantee virtually unlimited and tunable variation of the covalent structure of a polypeptide.
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