Journal
NEURON
Volume 40, Issue 2, Pages 415-425Publisher
CELL PRESS
DOI: 10.1016/S0896-6273(03)00630-5
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Neurons require long-distance microtubule-based transport systems to ferry vital cellular cargoes and signals between cell bodies and axonal or dendritic terminals. Considerable progress has been made on developing a molecular understanding of these processes and how they are integrated into normal neuronal functions. Recent work also suggests that these transport systems may fail early in the pathogenesis of a number of neurodegenerative diseases.
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