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AMERICAN JOURNAL OF CARDIOLOGY
Volume 92, Issue 8, Pages 977-980Publisher
EXCERPTA MEDICA INC
DOI: 10.1016/S0002-9149(03)00983-4
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Sixty-one patients with ST elevation acute myocardial infarction were randomized to receive open-label tirofiban in the emergency room before primary angioplasty versus glycoprotein IIb/IIIa inhibitors administered after initial coronary angiography. Early administration of tirofiban before primary angioplasty resulted in nonsignificant improvement in initial coronary flow (Thrombolysis In Myocardial Infarction trial grade 2 or 3 flow, 39% vs 27%, p >0.20). Patients receiving early tirofiban treatment were more likely to achieve complete (>70%) ST-segment resolution at 90 minutes (69% vs 44%, p = 0.07). (C) 2003 by Excerpta Medica, Inc.
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