Journal
HUMAN MOLECULAR GENETICS
Volume 12, Issue -, Pages R221-R227Publisher
OXFORD UNIV PRESS
DOI: 10.1093/hmg/ddg286
Keywords
-
Ask authors/readers for more resources
Methylation of cytosine in human DNA has been studied for over 60 years, but has only recently been confirmed as an important player in human disease. Rett syndrome is a neurological disorder caused by mutations in the MeCP2 protein, which has been shown to bind methylated DNA and repress transcription. This review will focus on experiments addressing the basic properties of MeCP2 and on mouse models of Rett syndrome that are starting to yield insights into this condition.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available