Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2003, Issue 20, Pages 3889-3895Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200300264
Keywords
antitumor agents; steroids; vitamins; inhibitors
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An increasing number of synthetic vitamin D analogues (deltanoids) are now being used as sensitive molecular biology probes and also as new drug candidates and new drugs for treatment of various human diseases. The design and stereocontrolled synthesis of such new deltanoids are guided by considering catabolism inhibition and by using large steroidal chirons and small steroid-derived chirons. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
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