Journal
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
Volume 39, Issue 1, Pages 45-50Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0928-8244(03)00185-8
Keywords
bacterial adherence; sialic acid; neuraminidase; urinary bladder epithelium
Categories
Ask authors/readers for more resources
The first step in the bacterial colonization and infection of uropathogenic Escherichia coli is adherence to uroepithelium. Over 80% of all urinary tract infections are caused by E coli. Uropathogenic E coli express several adherence factors including type 1 and P fimbriae, which mediate attachment to the uroepithelium through specific binding to different glycoconjugate receptors. We showed that P and type 1 fimbriae are not the sole adhesins on uropathogenic E coli and sialic acid also mediates nonspecific bacterial adherence of uropathogenic E coli and urinary bladder epithelium. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available