4.4 Article

Vulvodynia and proctodynia treated with topical baclofen 5 % and palmitoylethanolamide

Journal

ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Volume 290, Issue 2, Pages 389-393

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00404-014-3218-4

Keywords

Baclofen; Cream; Palmitoylethanolamide; Pain; Vulvodynia; Proctodynia; Pelvic; Glia

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The prevalence of idiopathic vulvodynia and proctodynia is high. Pain management with anti-depressants and anti-epileptics may induce undesirable side effects. Therefore, topical baclofen cream and palmitoylethanolamide might be new therapeutic options. A 33-year-old woman with intractable chronic vulvar and anal pain had to abstain from sexual intercourse and could neither cycle nor sit for more than 5 min. The patient did not respond to standard treatments. We prescribed a combination of topical baclofen 5 % and palmitoylethanolamide 400 mg, three times daily. After 3 months her symptoms decreased more than 50 % and sexual intercourse was possible again without pain. Topical baclofen and palmitoylethanolamide can be a viable treatment option in chronic vulvodynia and proctodynia.

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