Journal
OPTICS LETTERS
Volume 28, Issue 21, Pages 2061-2063Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.28.002061
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Funding
- NCRR NIH HHS [P41-RR14075] Funding Source: Medline
- NINDS NIH HHS [R29-NS38842, K25-NS44339] Funding Source: Medline
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We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance. (C) 2003 Optical Society of America.
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