Journal
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
Volume 29, Issue 6, Pages 594-600Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1023/B:RUBI.0000008902.36604.97
Keywords
antiviral activity; betulinic acid; isocyanates; carbamates; ureides; lupane triterpenoids
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Ureides and carbamates of betulinic acid and its derivatives were prepared in good yields by interaction of betulinic acid, betulonic acid, and betulonic acid 3-oxime with amines, amino acids, and alcohols. Ureides of betulonic acid containing L-Val and L-Met residues were found to be effective against herpes simplex type 1 virus.
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