Journal
ELECTROPHORESIS
Volume 24, Issue 21, Pages 3595-3606Publisher
WILEY
DOI: 10.1002/elps.200305648
Keywords
dynamic coating; electroosmosis; microchip; miniaturization; permanent coating; review; surface modification
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Different approaches and techniques for surface modification of microfluidic devices applied for microchip electrophoresis are reviewed. The main focus is on the improved electrophoretic separation by reducing analyte-wall interactions and manipulation of electroosmosis. Approaches and methods for permanent and dynamic surface modification of microfluidic devices, manufactured from glass, quartz and also different polymeric substrates, are described.
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