Journal
TETRAHEDRON LETTERS
Volume 44, Issue 45, Pages 8307-8310Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2003.09.063
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Microwave-assisted three-component cyclocondensation of barbituric acids 1, benzaldehyde 2 and alkyl nitriles 3 proceeds in the absence or presence of triethylamine to afford pyrano[2,3-d]pyrimidines 4 and 6-aminouracils 5 or 6-hydroxy-aminouracils 6 react with 2 and 3 under identical conditions to yield pyrido[2,3-d]pyrimidines 7, all in high yields. (C) 2003 Elsevier Ltd. All rights reserved.
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