Journal
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Volume 279, Issue 1, Pages 57-60Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00404-008-0631-6
Keywords
Uterine stromal sarcoma; Lung metastasis; Endocrine therapy; Goserelin; Anastrozole
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Approximately 50% of patients with low-grade endometrial stromal sarcoma (ESS) develop recurrent disease including mainly metastases of pelvis and lung. A solitary pulmonary metastasis of this disease is a rare phenomenon. After initial surgical treatment in 1990, a 28-year-old female developed solitary metastases of the lung in 1998 and 1999, which were surgically removed both times. The patient was then treated with goserelin for 2 years followed by anastrozole to date. She has since been disease-free. This case report emphasizes the importance of long-term follow-up and initial surgical treatment of low-grade ESS and suggests systemic hormonal therapy in case of recurrence.
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