4.7 Article

Highly selective oxidative cleavage of β-cyclodextrin-epoxide/aziridine complexes with IBX in water

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 68, Issue 23, Pages 9119-9121

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo034079c

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Water, an environmentally friendly reaction medium, has been utilized for the reaction of IBX with various epoxides 1 and aziridines 2 as their beta-cyclodextrin complexes to afford for the first time alpha-hydroxyketones 3 and alpha-aminoketones 4, respectively.

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