Journal
TETRAHEDRON
Volume 59, Issue 47, Pages 9419-9423Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2003.09.075
Keywords
anodic oxidation; ring-opening reaction; aeroplysinin; Verongia aerophoba
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An improved synthetic methodology of spiroisoxazolines by employing anodic oxidation of the corresponding phenol derivative has been established. An alternative efficient synthesis of aeroplysinin-1 1 has been achieved by employing the ring-opening reaction of spiroisoxazolines 10b, 10c as a key step. (C) 2003 Elsevier Ltd. All fights reserved.
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