Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 13, Issue 22, Pages 4011-4014Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2003.08.060
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Funding
- NHLBI NIH HHS [R01 HL052233-06, R01 HL052233-07, P01 HL048743-120008, HL 48743, R01 HL052233-05, R01 HL070274-01, R01 HL070274-02] Funding Source: Medline
- NIDDK NIH HHS [DK 38226, R01 DK062729-01A1] Funding Source: Medline
- NIGMS NIH HHS [GM 31278] Funding Source: Medline
- NINDS NIH HHS [P50 NS010828-290036, P01 NS010828-330036] Funding Source: Medline
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A series of 11,12-EET analogues were synthesized and compared using a human endothelial cell based TNF-alpha-induced VCAM-1 expression assay. The resulting data were used to map a putative recognition/binding domain for 11,12-EET. (C) 2003 Elsevier Ltd. All rights reserved.
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