4.4 Article

Rapid, easy copper-free Sonogashira couplings using aryl iodides and activated aryl bromides

Journal

TETRAHEDRON LETTERS
Volume 44, Issue 48, Pages 8653-8656

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2003.09.159

Keywords

Sonogashira; palladium; aryl iodides; aryl bromides; copper-free

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We present here an easy, rapid copper-free methodology for the Sonogashira coupling reaction. It works well for a range of aryl iodides and activated aryl bromides. (C) 2003 Elsevier Ltd. All rights reserved.

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