4.8 Article Proceedings Paper

Chemical communication among bacteria

Publisher

NATL ACAD SCIENCES
DOI: 10.1073/pnas.1934514100

Keywords

quorum sensing; autoinducer; cell-cell communication

Funding

  1. NIGMS NIH HHS [R01 GM065859, GM65859] Funding Source: Medline

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Cell-cell communication in bacteria is accomplished through the exchange of chemical signal molecules called autoinducers. This process, called quorum sensing, allows bacteria to monitor their environment for the presence of other bacteria and to respond to fluctuations in the number and/or species present by altering particular behaviors. Most quorum-sensing systems are species- or group-specific, which presumably prevents confusion in mixed-species environments. However, some quorum-sensing circuits control behaviors that involve interactions among bacterial species. These quorum-sensing circuits can involve both intra- and interspecies communication mechanisms. Finally, anti-quorum-sensing strategies are present in both bacteria and eukaryotes, and these are apparently designed to combat bacteria that rely on cell-cell communication for the successful adaptation to particular niches.

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