Journal
ORGANIC LETTERS
Volume 5, Issue 24, Pages 4541-4544Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol035463z
Keywords
-
Categories
Funding
- NCRR NIH HHS [1S10RR13886-01] Funding Source: Medline
- NHLBI NIH HHS [1R01-HL64799] Funding Source: Medline
Ask authors/readers for more resources
The octenediol linker used during automated oligosaccharide assembly is cleaved by olefin cross-metathesis. Until now, this linker could not be applied to sugars containing azides. A detailed study of the cleavage reaction served as basis for the development of a new protocol using the [(H(2)Imes)(3-Br-py)(2)(Cl)(2)Ru=CHPh] catalyst and 1-pentene. Efficient release of azide-protected carbohydrates from solid support can be readily achieved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available