Journal
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Volume 1630, Issue 2-3, Pages 138-143Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbaexp.2003.09.008
Keywords
FABP6; bile salt; intestinal absorption; transcription factor; FXR
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The ileal bile acid-binding protein (IBABP) is important for the reabsorption of bile salts in the distal small intestine. Studies with the human IBABP gene (FABP6, on chromosome 5q33.3-q34) defined the major transcription start site and identified conserved elements. A consensus element for the caudal-related homeobox factor CDX2 was functional in gel-shift assays and in transfection experiments. (C) 2003 Elsevier B.V. All rights reserved.
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