Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 13, Issue 6, Pages 651-658Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2003.10.013
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Funding
- NIGMS NIH HHS [R01 GM45668, R01 GM45398, R01 GM59290, R01 GM60518] Funding Source: Medline
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Mobile elements make up large portions of most eukaryotic genomes. They create genetic instability, not only through insertional mutation but also by contributing recombination substrates, both during and long after their insertion. The combination of whole-genome sequences and the development of innovative new assays to test the function of mobile elements have increased our understanding of how these elements mobilize and how their insertion impacts genome diversity and human disease.
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