Journal
JOURNAL OF VIROLOGY
Volume 77, Issue 24, Pages 13403-13406Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.77.24.13403-13406.2003
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Restriction of murine leukemia virus (MLV) was examined in cells from a range of mammals. All nonmurine restrictions were saturable blocks to N-tropic MLV infection, and several were prior to reverse transcription. We demonstrate restriction in cells from bat and show that if we express the murine restriction factor Fv1 in human cells, then Fv1, not the human host, defines the stage at which infection is blocked.
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