Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 68, Issue 26, Pages 10178-10180Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo034805b
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Regioselective and univocal Suzuki cross-coupling reactions performed on halopyridinyl boronic acids provide a flexible and versatile route to a multigram scale synthesis of 2,2'-dichloro-3,4'-bipyridine 14, which allows couplings with excess pyridin-3-yl boronic acid to give a new and efficient two-step rapid synthesis of nemertelline, the quaterpyridine neurotoxin isolated from a Hoplonemertine sea worm.
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