4.8 Article

Copper-mediated synthesis of N-acyl vinylogous carbamic acids and derivatives:: Synthesis of the antibiotic CJ-15,801

Journal

ORGANIC LETTERS
Volume 6, Issue 1, Pages 27-30

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0360041

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Funding

  1. NIGMS NIH HHS [GM-62842] Funding Source: Medline

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Copper(I)-mediated C-N bond formation has been employed to prepare both N-acyl vinylogous carbamic acids and ureas. The novel N-acyl vinylogous carbamic acid antibiotic, CJ-15,801, was synthesized using this methodology.

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