Journal
ORGANIC LETTERS
Volume 6, Issue 1, Pages 43-46Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol035995f
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Formamidine ureas display a rich manifold of reactivity. Thiols induce substitution at the carbonyl carbon to give thiolcarbamates; base-mediated alkylation and acylation occurs at the terminal urea nitrogen, and a new fragmentation/acylation pathway has been uncovered with isocyanates.
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