4.7 Article

Chloride complexation by heptapeptides: influence of C- and N-terminal sidechains and counterion

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 2, Pages 160-161

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b312008m

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Funding

  1. NIGMS NIH HHS [GM 63190] Funding Source: Medline

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The channel-forming diglycolylated heptapeptides containing the amino acid sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly have been found to complex chloride in CDCl3. The strength of the interaction depends on the terminal alkyl groups and on chloride's countercation.

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