4.4 Article

New synthesis of benzo[b]furan and indole derivatives from 1,1-dibromo-1-alkenes using a tandem Pd-assisted cyclization-coupling reaction

Journal

TETRAHEDRON LETTERS
Volume 45, Issue 5, Pages 907-910

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2003.11.118

Keywords

benzofuran; indole; palladium chemistry; tandem reaction; dibromo-alkenes

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We report a new flexible method for the synthesis of 2-functionalized benzo[b]furans and indoles from readily available o-(2,2-dibromovinyl)-phenol, -aniline or -acetanilide using a tandem Pd-assisted cyclization-coupling reaction. (C) 2003 Elsevier Ltd. All rights reserved.

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