Journal
TETRAHEDRON LETTERS
Volume 45, Issue 5, Pages 901-904Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2003.11.116
Keywords
alkaloid; Daphniphyllum glaucescens; daphniglaucin C; NMR.
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A novel Daphniphyllum alkaloid with an unprecedented tetracyclic ring system consisting of an octahydroindole and a hexahydroazulene rings, daphniglaucin C (1), has been isolated from the leaves of Daphniphyllum glaucescens and the structure and relative stereochemistry were elucidated on the basis of spectroscopic data. Daphniglaucin C (1) inhibited the polymerization of tubulin. (C) 2003 Elsevier Ltd. All rights reserved.
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