Journal
DIABETIC MEDICINE
Volume 21, Issue 3, Pages 203-207Publisher
WILEY
DOI: 10.1046/j.1464-5491.2003.01030.x
Keywords
acute phase response; complications; C-reactive protein; diabetes; inflammation; insulin resistance; sialic acid
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A few years ago a hypothesis was proposed suggesting that elements of the innate immune system, such as acute phase reactants, contribute to the development of Type 2 diabetes mellitus. Acute phase reactants such as C-reactive protein and sialic acid may thus predict risk of developing Type 2 diabetes mellitus, as well as being markers of diabetes microvascular and macrovascular complications. This article discusses these issues.
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