4.4 Article

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis

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ELSEVIER SCI LTD
DOI: 10.1016/j.berh.2003.09.010

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cytokine; therapy; antibody; anti-TNF

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The development of anti-TNF therapy is a key step forward in rheumatology as it is the first new therapy for based on investigating the molecular mechanisms of this disease. This chapter reviews how this discovery was made.

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