Journal
NATURE REVIEWS MICROBIOLOGY
Volume 2, Issue 2, Pages 141-150Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro819
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Even though significant advances have been made in understanding microbial diversity, most microorganisms are still only characterized by 'molecular fingerprints' and have resisted cultivation. Many different approaches have been developed to overcome the problems associated with cultivation of microorganisms because one obvious benefit would be the opportunity to investigate the previously inaccessible resources that these microorganisms potentially harbour.
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