Journal
RADIOLOGY
Volume 230, Issue 2, Pages 561-568Publisher
RADIOLOGICAL SOC NORTH AMERICA
DOI: 10.1148/radiol.2302020318
Keywords
carotid arteries, stenosis or obstruction; carotid arteries; ultrasound (US), contrast media
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B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069) was evaluated in human subjects with carotid artery disease. Results at contrast material-enhanced US angiography and duplex US were compared with those at conventional angiography. Both US angiography and duplex US accurately depicted stenoses of 70% or more compared with those depicted at conventional angiography. The percentage diameter stenosis of the internal carotid artery measured at US angiography strongly correlated with that measured at conventional angiography (r = 0.988). The percentage area stenosis measured at US angiography strongly correlated with ex vivo measurements of the resected carotid plaque at magnetic resonance imaging (r = 0.979). US angiography depicted unsuspected wall irregularities, ulceration, and dissection. (C) RSNA, 2003.
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