Journal
PROCEEDINGS OF THE NUTRITION SOCIETY
Volume 63, Issue 1, Pages 11-20Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1079/PNS2003312
Keywords
iron overload : iron deficiency : iron absorption
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Fe homeostasis is maintained by regulation of Fe absorption to balance largely unregulated body Fe losses. The majority of human subjects maintain relatively constant Fe stores; however, Fe deficiency and Fe overload are common conditions. Fe overload is frequently associated with mutations in genes of Fe metabolism. The present paper summarises present knowledge of these mutations as well as indicating other genes that animal studies have implicated as candidates for influencing body Fe stores.
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