Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 16, Issue 1, Pages 4-9Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2003.11.005
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Until very recently it was not known whether the invertebrate Caenorhabditis elegans was capable of mounting a specific immune response to protect itself from pathogens. It has only just become clear that this simple nematode in fact possesses a complex innate immune system, involving multiple signalling pathways and an armoury of antimicrobial proteins and peptides. Genetic and microarray approaches are now revealing the molecular cross-talk that exists between the different signalling cascades.
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