4.4 Article

Organic anion transport is the primary function of the SLC17/type I phosphate transporter family

Journal

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Volume 447, Issue 5, Pages 629-635

Publisher

SPRINGER-VERLAG
DOI: 10.1007/s00424-003-1087-y

Keywords

neurotransmitter transporter; organic anion transport; sialin; type I phosphate transporter; vesicular glutamate transporter

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Recently, molecular studies have determined that the SLC17/type I phosphate transporters, a family of proteins initially characterized as phosphate carriers, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitter glutamate to the degradation and metabolism of glycoproteins.

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