Journal
BIOTECHNIQUES
Volume 36, Issue 2, Pages 316-+Publisher
FUTURE SCI LTD
DOI: 10.2144/04362MT03
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Funding
- NHLBI NIH HHS [HL-28958] Funding Source: Medline
- NINDS NIH HHS [NS-29755] Funding Source: Medline
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Three different software packages for the probe-level analysis of high-density oligonucleotide microarray data were compared using an experiment-derived data set that was validated using real-time PCR. The efficiency with which these three programs could identify true positives in this data set was assessed. In addition, estimates of false-positive and false-negative rates were determined. The performance of the programs using very small data sets was also compared, and recommendations for use are suggested.
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